I went from using the 3x venom at a pretty high dosage to using the 1x cloud venom at a very low dosage. Can’t say for sure how much of a difference it has made but I will say it DOES NOT STING! Which is amazing bc the 3x regular venom was becoming way too painful and I would have to skip days or take weeks off. But this is definitely great when it comes to pain after injections. Plan on purchasing snow poly to do before these as well. Just wish there was larger sizes available!